Thoroughly clean your hands with soap and water to ensure a sterile environment before handling the pen or needle.
Remove the pen cap and check the medication. Ensure the solution is clear and free of particles. Select a new needle and peel off the paper tab.
Align the needle with the top of the pen and twist it on firmly until secure. This ensures a proper seal for safe injection.
Turn the dose knob to select a small dose (as instructed). Hold the pen upright and press the injection button to release air bubbles and prepare the flow.
Use the dose knob to select the correct dose as prescribed. Confirm the dose is visible in the dose window.
Recommended areas include the stomach (at least 2 inches away from the belly button), thigh, or back of the upper arm. Rotate injection sites weekly.
Insert the needle into your skin at a 90-degree angle. Press the injection button fully and hold for 5–10 seconds to ensure the full dose is delivered. Then, carefully remove and discard the needle in a sharps container.
If you're using Retatrutid for the first time, it’s essential to follow a gradual dosing plan to allow your body to adjust and minimize side effects.
Weeks 1–4: 2.5mg once weekly
Weeks 5–8: 5mg once weekly
Weeks 9–12: 7.5mg once weekly
Weeks 13 onward: 10mg once weekly
However, dosing should be guided by your body’s response — especially appetite suppression.
If your appetite remains well-suppressed on a lower dose (e.g. 2.5mg), you may remain on that dose longer (e.g. 6+ weeks) until appetite control begins to fade, then step up to the next dose.
Always allow your body to guide your progression. Only increase your dose when appetite suppression begins to fade.
2.5mg = Turn the dial 15 clicks
5mg = Turn dial to 30 clicks
7.5mg = Turn dial to 45 clicks
10mg = Turn dial to 60 clicks
You should inject once weekly on the same day each week. Ensure the correct dose is shown in the pen’s display window before injecting.
To maintain effectiveness and safety, always store your Alluvi Retatrutid pen according to the following guidelines:
Store in the refrigerator at 2°C to 8°C
Keep the pen in its original packaging to protect from light
Do not freeze the pen. If frozen, it must be discarded
You may store the used pen at room temperature (up to 15°C) for up to 4 hours
Keep away from direct heat, sunlight, and moisture
Always replace the pen cap after each use to prevent air exposure or leakage
Do not store with the needle attached
After completing all 4 doses or reaching 30 days after first use, dispose of the pen properly, even if some medication remains.
For disposal guidance or to report side effects, contact: Research@Alluvi.org
Make the most of your Retatrutide journey with these simple, effective tips covering usage, dosing, and storage.
Always prime the pen before the first dose by releasing a small amount into the air.
Use a new needle for every injection to avoid infections and clogged flow.
Inject slowly and hold the button down for at least 5 seconds to ensure full delivery.
Rotate injection sites weekly (stomach, thigh, or back of upper arm) to reduce skin irritation.
Press gently with gauze after injecting, but don’t rub the area.
Begin with 2.5mg and move up gradually only when needed.
If your appetite is well-suppressed, stay on the current dose longer before increasing.
Learn to use the dial:
15 clicks = 2.5mg
30 clicks = 5mg
45 clicks = 7.5mg
60 clicks = 10mg
Keep a simple log of what dose you took and when, especially during dose adjustments.
Keep unused pens refrigerated at 2–8°C until needed.
Once opened, store the pen at room temperature (max 30°C) for up to 30 days.
Always recap the pen and remove the needle after each use.
Never reuse needles or store the pen with a needle attached — this can lead to leaks or air entering the pen.
Dispose of used needles in a proper sharps container and discard the pen after 30 days or 4 doses.
For questions or side effect reporting, contact: Research@Alluvi.org
